1. 建立臺灣自己的參考序列 · 2. 為臺灣建立健康對照組的序列資訊 · 3. 作為基因填補法(genetic imputation)的模板,增加研究效益 · 4. 提供台灣健康族群低頻率變異(rare ... ... <看更多>
「taiwan biobank imputation」的推薦目錄:
taiwan biobank imputation 在 A high-resolution HLA imputation system for the ... - PubMed 的相關結果
A high-resolution HLA imputation system for the Taiwanese population: a study of the Taiwan Biobank. Pharmacogenomics J. 2020 Oct;20(5):695-704. doi: ... ... <看更多>
taiwan biobank imputation 在 Genetic profiles of 103,106 individuals in the Taiwan Biobank ... 的相關結果
To aid in the genotype imputation of East Asian samples in general and TWB samples in particular, we generated high-coverage whole-genome ... ... <看更多>
taiwan biobank imputation 在 Taiwan Biobank: A rich biomedical research database of the ... 的相關結果
Taiwan Biobank (TWB) is a prospective population study with >150,000 ... Retaining variants with an imputation quality INFO score > 0.6 and ... ... <看更多>
taiwan biobank imputation 在 台灣漢人族群中具有演化危害性的基因變異表徵關聯性分析 的相關結果
因此我們從台灣人體生物資料庫(Taiwan biobank, TWB)中取樣21,983個人,經過imputation差補分析和品管後,共有10,587,688個單一核苷酸多型性(SNP)。我們首先藉由CADD( ... ... <看更多>
taiwan biobank imputation 在 Taiwan Biobank: a rich biomedical research ... - medRxiv 的相關結果
The Taiwan Biobank (TWB) is an ongoing prospective study of over 150,000 ... Genotype generation, quality control, and imputation. ... <看更多>
taiwan biobank imputation 在 臺灣人體生物資料庫(Taiwan Biobank),歷經約十年可行性評估 ... 的相關結果
從2012年開始至2016年底,Taiwan Biobank已經完成募集近8萬名社區民眾志願 ... 作為基因填補法(genetic imputation)的模板,增加研究效益:建立台灣健康 ... ... <看更多>
taiwan biobank imputation 在 A high-resolution HLA imputation system for ... - ResearchGate 的相關結果
In this study, a subset of 1012 individuals from the Taiwan Biobank (TWB) who underwent both whole-genome SNP array and NGS-based HLA typing were used to ... ... <看更多>
taiwan biobank imputation 在 ChienWei Lin - Taiwan Biobank, Academia Sinica - LinkedIn 的相關結果
Taipei, Taiwan. • Created reference panel from WGS data for genotype imputation • Established the imputation pipeline for genotyping data ... <看更多>
taiwan biobank imputation 在 生醫服務入口平台 的相關結果
為臺灣人體生物資料庫(Taiwan Biobank)主持人,透過國網計算與儲存服務完成許多釋出資料分析,包含完成1500人全基因體定序(WGS)分析、完成超過11萬人的Genotype imputation ... ... <看更多>
taiwan biobank imputation 在 DNA+甲基化插補方法之比較研究 - Airiti Library華藝線上圖書館 的相關結果
A comparative study on DNA methylation imputation methods ... DNA methylation ; Taiwan Biobank ; K Nearest Neighbors impute algorithm ; Multiple Imputation ... ... <看更多>
taiwan biobank imputation 在 "Comparison of Multiple Imputation Algorithms Used the ... 的相關結果
Accordingly, to provide data specific to Taiwan, we established a large-scale ... and Verification Using Whole-Genome Sequencing in the CMUH Genetic Biobank ... ... <看更多>
taiwan biobank imputation 在 A high-resolution HLA imputation system for the ... - X-MOL 的相關結果
In this study, a subset of 1012 individuals from the Taiwan Biobank (TWB) who underwent both whole-genome SNP array and NGS-based HLA typing ... ... <看更多>
taiwan biobank imputation 在 國立臺灣大學生物資源暨農學院生物機電工程學系碩士論文 的相關結果
disease based on the Taiwan Biobank database (TWB). After performing quality control and genotype imputation of the TWB data set, the significant SNPs were ... ... <看更多>
taiwan biobank imputation 在 Genome-Wide Association Study for eGFR in a Taiwanese ... 的相關結果
The quality control filtering and genotype imputation resulted in 10,008 Taiwan Biobank participants and 6,553,511 variants for final analyses. ... <看更多>
taiwan biobank imputation 在 SNP Array Imputation - China Medical University Hospital 的相關結果
SNP Array Imputation ... the data of 1361 Taiwanese Whole Genome Sequence (WGS) released by Taiwan Biobank ... Operational procedure of SNP array imputation ... <看更多>
taiwan biobank imputation 在 台灣人體生物資料庫發展與實務應用 的相關結果
Why Taiwan Biobank? ... Taiwan biobank制定80個SOP + 200個文件來執行 ... Y.-H. (2020) A high-resolution HLA imputation system for the Taiwanese population:. ... <看更多>
taiwan biobank imputation 在 國立清華大學108 學年第2 學期新開課程課程大綱 的相關結果
台灣 人體資料庫分析. 科目英文名稱. Taiwan biobank analysis. 任課教師. 王群超助理教授/分醫所. 擋修科目. 擋修分數. ※下列各欄由任課教師提供※. 一、課程說. ... <看更多>
taiwan biobank imputation 在 The Taiwan Biobank Provides Insights into the Health and ... 的相關結果
In summary, the authors generated a large reference panel that greatly improved the imputation accuracy of SNP genotyping data and designed a ... ... <看更多>
taiwan biobank imputation 在 Overcoming the challenges of imputation of rare variants in a ... 的相關結果
Taiwan Biobank : making cross-database convergence possible in the Big Data era. Gigascience 2018;7:1-4. Submitted Jun 23, 2020. Accepted for publication Jul 15, ... ... <看更多>
taiwan biobank imputation 在 Genome-wide analyses identify novel risk loci for cluster ... 的相關結果
... from the Taiwan Biobank. Genotyping was conducted with the Axiom Genome-Wide Array TWB chip, followed by whole genome imputation. ... <看更多>
taiwan biobank imputation 在 Genome-wide association study identifies genetic risk loci for ... 的相關結果
... information for more than 21000 subjects from the Taiwan Biobank. ... Whole-genome imputation was conducted using a reference panel ... ... <看更多>
taiwan biobank imputation 在 Axiom Biobank Genotyping Arrays - Thermo Fisher Scientific 的相關結果
These content modules exist within the Axiom Genomic Database, which covers 26 million SNPs and indels. GWAS. Intelligent marker selection enables imputation of ... ... <看更多>
taiwan biobank imputation 在 《Nature》UK Biobank 15萬人全基因體定序帶來疾病新見解 的相關結果
研究團隊表示,透過這些單倍型參考組(haplotype reference panel),能讓我們針對由三個以上定序個體所帶有大多數變異,執行可靠的試算(imputation)。 此外 ... ... <看更多>
taiwan biobank imputation 在 Comprehensive characterization of pharmacogenes in a ... 的相關結果
A high-resolution HLA imputation system for the Taiwanese population: a study of the taiwan biobank. Pharmacogenomics J. 20, 695–704. ... <看更多>
taiwan biobank imputation 在 Genetic Variants at the APOE Locus Predict Cardiometabolic ... 的相關結果
A total of 81387 Taiwan Biobank (TWB) participants were enrolled to undergo ... Genome-wide genotype imputation was performed using SHAPEIT and IMPUTE2, ... ... <看更多>
taiwan biobank imputation 在 Using PLINK for Genome-Wide Association Study 的相關結果
Using PLINK for. Genome-Wide Association Study. Chien-Wei Lin. Bioinformatic Specialist, Taiwan Biobank. Page 2. Page 3. • Human Genome Project (1990-2003). ... <看更多>
taiwan biobank imputation 在 Population structure of Han Chinese in the modern Taiwanese ... 的相關結果
The Taiwan Biobank (TWB) aims to build a nationwide research database that ... SNPs covered by Taiwan View has been extended by imputation from the original ... ... <看更多>
taiwan biobank imputation 在 【專欄】臺灣人體生物資料庫近年釋出成果(十一) 的相關結果
HLA插補分析(imputation analyses)顯示,與DQB1*06:02連鎖不平衡的HLA-DRB1*15:01也增加了HCC的 ... 名聽力正常的漢族受試者和台灣人體生物資料庫(Taiwan Biobank ... ... <看更多>
taiwan biobank imputation 在 Large‐scale genome‐wide association study identifies HLA ... 的相關結果
... associated with chronic HBV infection: a study from Taiwan Biobank ... The human leucocyte antigen (HLA) imputation was performed after ... ... <看更多>
taiwan biobank imputation 在 Phenome-wide analysis of Taiwan Biobank reveals novel ... 的相關結果
Detailed demographic data are presented in Supplementary. Data 2. About 6 million imputed autosomal SNPs passed our QC criteria and were tested ... ... <看更多>
taiwan biobank imputation 在 Integration of genome-wide association study and expression ... 的相關結果
... was extracted from blood and evaluated by the GWAS of Taiwan Biobank Array. ... After imputation, strong signals were exhibited by rs10822312 (P = 1.80 ... ... <看更多>
taiwan biobank imputation 在 SAD - AHA Journals 的相關結果
METHODS: We genotyped 190 unrelated BrS patients using the TWB Array, and Taiwan Biobank was used as controls. SNPs not included in the array were imputed ... ... <看更多>
taiwan biobank imputation 在 Blood donor biobank and HLA imputation as a resource of ... 的相關結果
the imputed alleles in the present biobank cohort and allele frequencies of the ... Taiwanese population: a study of the Taiwan Biobank. ... <看更多>
taiwan biobank imputation 在 Global Biobank Meta-analysis Initiative: Powering genetic ... 的相關結果
BioBank, Qatar Biobank, The QSkin Sun and Health Study, Taiwan Biobank, ... and genotypes (genotyping platforms and imputation. Figure 1. ... <看更多>
taiwan biobank imputation 在 Genome-wide association study reveals susceptibility loci for ... 的相關結果
The Taiwan Biobank (TWB) is a general population-based public health research ... Using the whole genome imputation data, two SNPs identical to the real ... ... <看更多>
taiwan biobank imputation 在 LmTag: functional-enrichment and imputation-aware tag SNP ... 的相關結果
The performance of imputation is affected by three main factors, ... population based on 10,000 participants in the taiwan biobank project. ... <看更多>
taiwan biobank imputation 在 UK Biobank Phasing and Imputation Documentation 的相關結果
This document describes the analysis carried out to perform genotype imputation for the interim release of the UK Biobank (UKB) genotype data. ... <看更多>
taiwan biobank imputation 在 生物資料庫對醫療產業之影響 的相關結果
Academia Sinica, Taiwan ... Biobank. ▫ A biorepository that stores biological samples for use in research ... Reference for imputation. ... <看更多>
taiwan biobank imputation 在 利用基因定序技術與大型基因體數據庫探討 罕見遺傳疾病與 ... 的相關結果
Basal characteristics of Taiwan Biobank participants. Table 10. ... genotypic data includes whole-genome genotyping and imputed genotypes were applied for. ... <看更多>
taiwan biobank imputation 在 Genome-wide association meta-analysis of 88250 individuals ... 的相關結果
A multi-trait analysis of glaucoma on UK Biobank (UKB) and ... The imputed data has been aligned to the + strand of the reference and SNP ... ... <看更多>
taiwan biobank imputation 在 HLA imputation and its application to genetic and molecular ... 的相關結果
Thus, HLA imputation, a method to infer HLA types from regional single ... for the Taiwanese population: a study of the Taiwan Biobank. ... <看更多>
taiwan biobank imputation 在 Serum Urate and Risk of Chronic Kidney Disease 的相關結果
Imputation was performed using a population-specific reference haplotype panel of 1445 genome sequences from the Taiwan Biobank. ... <看更多>
taiwan biobank imputation 在 Global Biobank Meta-Analysis Initiative Brings ... - GenomeWeb 的相關結果
Through a genetic discovery strategy incorporating genotyping, sequencing, and imputation-based approaches, HUNT researchers have discovered ... ... <看更多>
taiwan biobank imputation 在 A Genome-Wide Asso - MDPI 的相關結果
genome-wide study of the Taiwan Biobank containing the data of 2533 healthy ... For clustered SNPs with P < 1 × 10−5, we used imputation by ... ... <看更多>
taiwan biobank imputation 在 Link in body mass index, WNT16 rs2908004 & osteoporosis 的相關結果
Imputation was carried out using the IMPUTE2 (v2.3.1) program. ... Taiwan Biobank provided phenotypic and genetic data for this study. ... <看更多>
taiwan biobank imputation 在 Association of Unhealthy Lifestyle and Childhood Adversity ... 的相關結果
We conducted this study using data from UK Biobank (UKB), ... Multiple imputations by chained equations were used to impute missing values ... ... <看更多>
taiwan biobank imputation 在 Associations Between Body Mass Index, WNT16 rs2908004 ... 的相關結果
... WNT16 rs2908004 and Osteoporosis: Findings from Taiwan Biobank ... Imputation was carried out using the IMPUTE2 (v2.3.1) program. ... <看更多>
taiwan biobank imputation 在 Region: chr15:98646000-98654302 - GWAS Catalog 的相關結果
... Genome-wide association study in the Taiwan biobank identifies four novel ... via high-density imputation of GWASs in individuals of African ancestry. ... <看更多>
taiwan biobank imputation 在 李美璇教授 的相關結果
chronic HBV infection: a study from Taiwan Biobank. Aliment Pharmacol Ther, 2020; ... A high-resolution HLA imputation system for the Taiwanese population:. ... <看更多>
taiwan biobank imputation 在 Taiwan Biobank: a project aiming to aid Taiwan's transition ... 的相關結果
Taking the UK Biobank's experience as the main example, the Taiwan Biobank aims to collect the DNA of a large group of people on the population ... ... <看更多>
taiwan biobank imputation 在 Azure HPC to accelerate Genome-wide Analysis study (GWAS) 的相關結果
Covid-19 genotype samples are fetched from UK Biobank. ... Genotype Imputation generates missing genotypes to improve data quality, which in ... ... <看更多>
taiwan biobank imputation 在 Multiple measures of depression to enhance validity of major ... 的相關結果
Most genetic correlations between UK Biobank and the Psychiatric ... The UK Biobank imputed genotype data to the Haplotype Reference ... ... <看更多>
taiwan biobank imputation 在 Lack of association of genetic variants for diabetic retinopathy ... 的相關結果
recruited from the Taiwan Biobank. Detailed information ... Genotyping, imputation, quality control and population substructure. ... <看更多>
taiwan biobank imputation 在 臺灣人體生物資料庫 - 健康跟著走 的相關結果
TWB2, Taiwan Biobank, 2nd batch, N=1,901. Reference ... 38 0 . 38 2 . 36 0 . ... 臺灣人體生物資料庫TWBv1.0基因型差補(Genotype imputation)hg38版本開放釋出. ... <看更多>
taiwan biobank imputation 在 國立臺北護理健康大學健康事業管理研究所 的相關結果
Background: In recent years, Taiwan has been promoting precision ... Biobank),提供國內研究者生物檢體與臨床資料,以進行生物醫學領域相關研. ... <看更多>
taiwan biobank imputation 在 Genome Data Analysis - 第 253 頁 - Google 圖書結果 的相關結果
... and hotspot 5 Basic information regarding genotype imputation 5 Selection ... Some SNPs in ThaiSNP2, Taiwan Biobank, HGDP-CEPH Database, and ALFRED can ... ... <看更多>
taiwan biobank imputation 在 目錄 - Taiwan Biobank 台灣人體生物資料庫 的相關結果
基因型插補(imputation)是預測樣本中未直接定型的基因型的一個過程,這些經由電腦. 模擬出來的基因型能夠增加SNP 與疾病相關性檢定的SNP 數量,增加研究的檢定力。 ... <看更多>